Agriculture & Biotechnology Research Center
Tan Haibo
Highest Education
Post
Phone 020-37252958
Email tanhaibo@scbg.ac.cn
Office Xingke Road #723, Tianhe District, Guangzhou
Education and Appointments

  Education 

    


  2009.09-2014.06Ph.D. in Organic Chemistry (Supervised by Prof. Zhen Yang), College of Chemistry and Molecular Engineering, Peking University; 

  2005.09-2009.06Bachelor of Science in Chemistry Science, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology, China. 

  Professional Experience 

    


  2014.07-2016.07: Assistant Researcher, South China Botanical Garden, Chinese Academy of Sciences; 

  2016.08-now: Associated Researcher, South China Botanical Garden, Chinese Academy of Sciences. 

Research Interest

  Bioactive meaningful natural product discovery; 

  Natural product skeleton oriented synthetic methodology development. 

  Total synthesis and structure-activity relationship study; 

  Drug discovery. 

Public Services
 
Honors
 
Selected Publication

  [1] Liu, H. X.; Zhao, L. Y.; Yuan, Y. F.; Xu, Z. F.; Chen, K.*; Qiu, S. X.*; Tan, H. B.* Potassium thioacids mediated selective amide and peptide constructions enabled by visible light photoredox catalysis. ACS Catal. 2016, 6, 1732-1736. (*Corresponding author) 

  [2] Liu, H. X.; Dang, Y. Q.; Yuan, Y. F.; Xu, Z. F.; Qiu, S. X.*; Tan, H. B.* Diacyl disulfide: a reagent for chemoselective acylation of phenols enabled by 4-(N,N-dimethylamino)pyridine catalysis. Org. Lett. 2016, 18, 5584-5587. (*Corresponding author) 

  [3] Tan, H. B.; Zheng, C.; Liu, Z.; Wang, D. Z.* Biomimetic total syntheses of Linderaspirone A and Bi-linderone and revisions of their biosynthetic pathways. Org. Lett. 2011, 13, 2192-2195.  

  [4] Tan, H. B.; Liu, H. X.; Chen, X. Z.; Yuan, Y. F.; Chen, K.*; Qiu, S. X.* Concise construction of the tricyclic core of bullataketals enabled by a biomimetic intermolecular (3+3) type cycloaddition. Org. Lett. 2015, 17, 4050-4053. 

  [5] Gong, L.#; Tan, H. B.#; Chen, F.; Li, T. T.; Zhu, J. Y.; Jian, Q. J.; Yuan, D. B.; Xu, L. X.; Hu, W. Z.; Jiang, Y. M.; Duan, X. W. Novel synthesized 2,4-DAPG analogues: antifungal activity, mechanism and toxicology. Sci. Rep. 2016, 6, 32266. (#The same contribution) 

  [6] Tan, H. B.; Liu, H. X.; Zhao, L. Y.; Yuan, Y.; Li, B. L.; Jiang, Y. M.; Gong, L.*; Qiu, S. X.* Structure-activity relationships and optimization of acyclic acylphloroglucinol analogues as novel antimicrobial agents. Eur. J. Med. Chem. 2017, 125, 492-499. 

  [7] Tan, H. B.*; Liu, H. X.; Chen, X. Z.; Chen, H. Y.; Qiu, S. X.* Racemic total synthesis of dactyloidin and demethyldactyloidin through the DL-proline catalyzed Knoevenagel condensation/[4 + 2] cycloaddition cascade. Org. Biomol. Chem. 2015, 13, 9977-9983.  

  [8] Liu, H. X.; Chen,,K.; Yuan, Y.; Xu, Z. F.; Tan, H. B.*; Qiu, S. X.* Rhodomentones A and B, novel meroterpenoids with unique NMR characteristics from Rhodomyrtus tomentosa. Org. Biomol. Chem. 2016, 14, 7354-7360. (*Corresponding author) 

  [9] Liu, H. X.; Zhang, W. M.; Xu, Z. F.; Chen, Y. C.; Tan, H. B.*; Qiu, S. X.* Isolation, synthesis, and biological activity of temetosenol A from the leaves of Rhodomyrtus tomentosa. RSC Adv. 2016, 6, 25882-25886. (*Corresponding author) 

  [10] Liu, H. X.; Chen, K.; Tang, G. H.; Yuan, Y. F.; Tan, H. B.*; Qiu, S. X.* Isolation and biomimetic total synthesis of tomentodiones A-B, terpenoid-conjugated phloroglucinols from the leaves of Rhodomyrtus tomentosa. Rsc Adv. 2016, 6, 48231-48236. (*Corresponding author) 

  [11] Tan, H. B.*; Chen, X. Z.; Chen, H. Y.; Liu, H. X.; Qiu, S. X.* Proline-catalyzed Knoevenagel condensation/[4+2] cycloaddition cascade reaction: application to formal synthesis of averufin. Eur. J. Org. Chem. 2015, 22, 4956-4963. (*Corresponding author) 

  [12] Tan, H. B.; Chen, X. Z.; Liu, Z.; Wang, D. Z.* Total synthesis of angelone enabled by a remarkable biomimetic sequence. Tetrahedron 2012, 68, 3952-3955. 

  [13] Zhang,Q.; Liu, H. X.; Tan, H. B.*; Qiu, S. X.* Novel highly oxygenated and rare B-ring-seco-ent-diterpene glucosides from the seeds of Prinsepia utilis. Tetrahedron 2015, 71, 9415-9419. (*Corresponding author) 

  [14] Liu, H. X.#; Tan, H. B.#; He, M. T.; Li, L.; Wang, Y. H.; Long, C. L.* Isolation and synthesis of two hydroxychavicol hetreodimers from Piper nudibaccatum. Tetrahedron 2015, 71, 2369-2375. (#The same contribution) 

  [15] Liu, H. X.; Chen, K.; Liu, Y.; Li, C.; Wu, J. W.; Xu, Z. F.; Tan, H. B.*; Qiu, S. X.* Callviminols A-E, new terpenoid-conjugated phloroglucinols from the leaves of Callistemon viminalis. Fitoterapia 2016, 115, 142-147. (*Corresponding author) 

  [16] Liu, H. X.; Chen, Y. C.; Liu, Y.; Zhang, W. M.; Wu, J. W.; Tan, H. B.*; Qiu, S. X.* Acylphloroglucinols from the leaves of Callistemon viminalis. Fitoterapia 2016, 114, 40-44. (*Corresponding author) 

  [17] Liu, H. X.#; Tan, H. B.#; Liu, Y.; Chen, Y. C.; Li, S. N.; Sun, Z. H.; Li, H. H.; Qiu, S. X.; Zhang, W. M.* Three new highly-oxygenated metabolites from the endophytic fungus Cytospora rhizophorae A761. Fitoterapia 2017, 117, 1-5. (#The same contribution) 

  [18] Li, J.; Zhang, J.; Tan, H. B.; Wang, D. Z. Visible-light-promoted vinylation of tetrahydrofuran with alkynes through direct C–H bond functionalization. Org. Lett. 2015, 17, 2522-2525. 

  [19] Wang, X. B.; Zhang, Y. B.; Tan, H. B.; Wang, Y. C.; Han, P.; Wang, D. Z. Enantioselective organocatalytic mannich reactions with autocatalysts and their mimics. J. Org. Chem. 2010, 75, 2403-2406. 

  [20] Song, J. L.; Yuan, Y.; Tan, H. B.; Wu, J. W.; Huang, R. M.; Li, H.; Xu, Z. F.; Na, N.; Qiu, S. X. Euryachins A and B, a new type of diterpenoids from Eurya chinensis with potent NO production inhibitory activity. RSC Adv. 2016, 6, 85958-85961. 

  [21] Liu, H. X.; He, M. T.; Tan, H. B.; Gu, W.; Yang, S. X.; Wang, Y. H.; Li, L.; Long, C. L. Xanthine oxidase inhibitors isolated from Piper nudibaccatum. Phytochem. Lett. 2015, 12, 133-137. 

  [22] Liu, H. X.; Tan, H. B.; Qiu, S. X.* Antimicrobial acylphloroglucinols from the leaves of Rhodomyrtus tomentosa. J. Asian Nat. Prod. Res. 2016, 535-541. 

  [23] Song, J. L.; Yuan, Y.; Tan, H. B.; Huang, R. M.; Liu, H. X.; Xu, Z. F.; Qiu, S. X.* Anti-inflammatory and antimicrobial coumarins from the stems of Eurya chinensis. J. Asian Nat. Prod. Res. 2016, DOI: 10.1080/10286020.2016.1191474.